The science behind SN-2 palmitate & infant health

Human Milk Oligosaccharides (HMOs) are widely recognised for their vital role in infant health and there’s now a growing body of evidence highlighting the significant benefits of SN-2 palmitate. In this podcast, neonatal nurse, Dr Janet Green, joins us to delve into the latest evidence on these essential nutrients found in premium infant formulas. You’ll learn exactly what SN-2 palmitate is, why its structure is so important and the impact it has on gut health, calcium and fat absorption, and bone mineral content. Janet also offers valuable tips on interpreting the latest research and expert guidelines.

Hosted by Dr Jane Winter

Biography

 

Dr Janet Green is a Senior Lecturer at Notre Dame University of Australia, and an adjunct Senior Lecturer at The University of Tasmania, based in Sydney. Janet has qualifications in Midwifery, Lactation, Neonatal intensive care, Paediatric intensive care, Emergency Paediatrics and Child and family health. Janet has many years’ experience as a neonatal nurse, and has retained strong ties to the clinical community. Janet holds Masters Degrees in Nursing Education, Bioethics and E-Learning. Her PhD explored the ethical issues surrounding caring for extremely premature babies. She is currently completing the final stages of a Doctor of Education degree, and for several years she was the Nurse Adviser to the NSW Health Care Complaints Commission (HCCC).

 

In this episode, we discuss:

  • The role of SN-2 palmitate in infant health
  • What to look for in a premium infant formula
  • Where to find current guidelines & expert recommendations

Additional resources

  • Click here to watch the Paediatric Symposium: Navigating nutrition in infants and children
  • Click here to view a research update on SN-2 palmitate

References

  • Béghin L, Marchandise X, Lien E, et al. Growth, stool consistency and bone mineral content in healthy term infants fed sn-2-palmitate-enriched starter infant formula: A randomized, double-blind, multicentre clinical trial. Clin Nutr. 2019;38(3):1023-1030. doi:10.1016/j.clnu.2018.05.015
  • Yao M, Lien EL, Capeding MR, et al. Effects of term infant formulas containing high sn-2 palmitate with and without oligofructose on stool composition, stool characteristics, and bifidogenicity. J Pediatr Gastroenterol Nutr. 2014;59(4):440-448. doi:10.1097/MPG.0000000000000443
  • Guo D, Li F, Zhao J, et al. Effect of an infant formula containing sn-2 palmitate on fecal microbiota and metabolome profiles of healthy term infants: a randomized, double-blind, parallel, controlled study. Food Funct. 2022;13(4):2003-2018. Published 2022 Feb 21. doi:10.1039/d1fo03692k

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This episode includes discussion of infant formula and formula feeding and is intended for HCPs only. Breastfeeding is best for babies and a decision not to breastfeed can be difficult to reverse. Social and financial implications should be considered when discussing formula feeding. Views, opinions or recommendations today are those of the speaker, and do not necessarily represent those of Dietitian Connection.

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